—— Alexander Gaus
—— Oleg M
—— susan Rustiguel
—— Holly Shane
—— Alex Clinton
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|Product Name:||Coluracetam||CAS No.:||135463-81-9|
|Molecular Weight:||341.40||Molecular Formula:||C19H23N3O3|
|Purity:||99% Min.||Standard:||Pharmaceutical Grade|
Coluracetam powder natural Nootropics CAS No. 135463-81-9 Pharmaceutical Grade MKC-231
Coluracetam appears to interact with a process known as high affinity choline uptake (HACU for short), which is the rate-limiting step of drawing choline into a neuron for synthesis into the neurotransmitter acetylcholine. Increasing the HACU rate appears to increase the activity of cholinergic neurons, so it is a desired target for cognitive enhancement.
Interventions in rats (as there is no human evidence currently) support the usage of coluracetam at very low oral doses to preserve HACU that is otherwise impaired by the use of research drugs that are known to impair HACU. The limited evidence looking at the inherent effects of coluracetam on the HACU of normal neurons has failed to find any significant interaction.
Coluracetam has also been noted to associate with choline transporters physically, but it is not known exactly what it does once associated.
Overall, there is currently insufficient evidence to support the usage of coluracetam for cognitive enhancement. Further studies are needed to see if it has a therapeutic role in instances where HACU may be impaired (such as Alzheimer's disease).
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